{"id":1466,"date":"2024-08-19T14:51:40","date_gmt":"2024-08-19T13:51:40","guid":{"rendered":"https:\/\/heliusstudy.nl\/?post_type=publicatie&#038;p=1466"},"modified":"2024-08-19T14:51:41","modified_gmt":"2024-08-19T13:51:41","slug":"differences-in-sars-cov-2-infections-during-the-first-and-second-wave-of-sars-cov-2-between-six-ethnic-groups-in-amsterdam-the-netherlands-a-population-based-longitudinal-serological-study","status":"publish","type":"publicatie","link":"https:\/\/heliusstudy.nl\/en\/publicatie\/differences-in-sars-cov-2-infections-during-the-first-and-second-wave-of-sars-cov-2-between-six-ethnic-groups-in-amsterdam-the-netherlands-a-population-based-longitudinal-serological-study\/","title":{"rendered":"Differences in SARS-CoV-2 infections during the first and second wave of SARS-CoV-2 between six ethnic groups in Amsterdam, the Netherlands: A population-based longitudinal serological study"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Background:&nbsp;<\/strong>Surveillance data in high-income countries have reported more frequent SARS-CoV-2 diagnoses in ethnic minority groups. We examined the cumulative incidence of SARS-CoV-2 and its determinants in six ethnic groups in Amsterdam, the Netherlands.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Methods:&nbsp;<\/strong>We analysed participants enrolled in the population-based HELIUS cohort, who were tested for SARS-CoV-2-specific antibodies and answered COVID-19-related questions between June 24-October 9, 2020 (after the first wave) and November 23, 2020-March 31, 2021 (during the second wave). We modelled SARS-CoV-2 incidence from January 1, 2020-March 31, 2021 using Markov models adjusted for age and sex. We compared incidence between ethnic groups over time and identified determinants of incident infection within ethnic groups.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Findings:&nbsp;<\/strong>2,497 participants were tested after the first wave; 2,083 (83\u00b74%) were tested during the second wave. Median age at first visit was 54 years (interquartile range=44-61); 56\u00b76% were female. Compared to Dutch-origin participants (15\u00b79%), cumulative SARS-CoV-2 incidence was higher in participants of South-Asian Surinamese (25\u00b70%; adjusted hazard ratio [aHR]=1\u00b766; 95%CI=1\u00b716-2\u00b740), African Surinamese (28\u00b79%, aHR=1\u00b797; 95%CI=1\u00b737-2\u00b783), Turkish (37\u00b70%; aHR=2\u00b767; 95%CI=1\u00b789-3\u00b778), Moroccan (41\u00b79%; aHR=3\u00b713; 95%CI=2\u00b722-4\u00b742), and Ghanaian (64\u00b76%; aHR=6\u00b700; 95%CI=4\u00b733-8\u00b730) origin. Compared to those of Dutch origin, differences in incidence became wider during the second versus first wave for all ethnic minority groups (all p-values for interaction&lt;0\u00b705), except Ghanaians. Having household members with suspected SARS-CoV-2 infection, larger household size, and low health literacy were common determinants of SARS-CoV-2 incidence across groups.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Interpretation:&nbsp;<\/strong>SARS-CoV-2 incidence was higher in the largest ethnic minority groups of Amsterdam, particularly during the second wave. Prevention measures, including vaccination, should be encouraged in these groups.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background:&nbsp;Surveillance data in high-income countries have reported more frequent SARS-CoV-2 diagnoses in ethnic minority groups. We examined the cumulative incidence of SARS-CoV-2 and its determinants in six ethnic groups in Amsterdam, the Netherlands. Methods:&nbsp;We analysed participants enrolled in the population-based HELIUS cohort, who were tested for SARS-CoV-2-specific antibodies and answered COVID-19-related questions between June 24-October [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":true},"publications_year":[23],"thema":[44],"class_list":["post-1466","publicatie","type-publicatie","status-publish","hentry","publications_year-23","thema-infectious-disease"],"acf":[],"_links":{"self":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publicatie\/1466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publicatie"}],"about":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/types\/publicatie"}],"wp:attachment":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/media?parent=1466"}],"wp:term":[{"taxonomy":"publications_year","embeddable":true,"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publications_year?post=1466"},{"taxonomy":"thema","embeddable":true,"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/thema?post=1466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}