{"id":1657,"date":"2024-08-28T14:14:03","date_gmt":"2024-08-28T13:14:03","guid":{"rendered":"https:\/\/heliusstudy.nl\/?post_type=publicatie&#038;p=1657"},"modified":"2024-08-28T14:14:04","modified_gmt":"2024-08-28T13:14:04","slug":"targeted-screening-for-viral-hepatitis-among-various-ethnic-groups-in-amsterdam-the-netherlands","status":"publish","type":"publicatie","link":"https:\/\/heliusstudy.nl\/en\/publicatie\/targeted-screening-for-viral-hepatitis-among-various-ethnic-groups-in-amsterdam-the-netherlands\/","title":{"rendered":"Targeted Screening for Viral Hepatitis Among Various Ethnic Groups in Amsterdam, the Netherlands"},"content":{"rendered":"\n<p><strong>Background<\/strong>: A significant portion of individuals with hepatitis B virus (HBV) or hepatitis C virus (HCV) in the Netherlands remain undiagnosed, with a majority from migrant backgrounds.<\/p>\n\n\n\n<p><strong>Objectives<\/strong>: This study explored whether targeting HBV\/HCV screening among individuals with metabolic risk factors enhances screening efficacy within a diverse ethnic cohort.<\/p>\n\n\n\n<p><strong>Methods<\/strong>: Participants from six ethnic backgrounds were enlisted from the population-based, prospective HELIUS study in theNetherlands. Included were participants at elevated risk for non-alcoholic fatty liver disease (NAFLD), identified by elevated non-invasive tests (NITs) and\/or metabolic risk factors, who were then tested for HBV\/HCV. We evaluated screening efficiency, defined as the prevalence of HBV\/HCV, by implementing two targeted screening strategies: (1) Testing individuals with elevated NITs; and (2) those with metabolic risk factors. These strategies were compared to a generic testing approach previously utilized in a subset of HELIUS participants. For non-Dutch origin participants, analyses were stratified based on the HBsAg-prevalence in their region of origin: Low (&lt; 2%) and intermediate (2 &#8211; 8%). <\/p>\n\n\n\n<p><strong>Results<\/strong>: The study included 346 participants at risk for NAFLD, predominantly of Surinamese (n = 180; 45%), Dutch (n = 103; 26%), or Ghanaian (n = 63; 16%) origin. The generic testing approach encompassed 3,050 individuals. Among individuals from low and intermediate HBV-endemic countries, HBsAg-revalence was 4.7% and 5.3% for those with elevated NITs, 3.9%, and 3.5% for those with metabolic risk factors, and 0.8% and 3.7% for generic testing, respectively. Regarding HCV, two individuals were anti-CV-positive, with none being HCV-RNA-positive.<\/p>\n\n\n\n<p><strong>Conclusions<\/strong>: Targeted screening based on metabolic risk factors or elevated NITs may be more efficient than generic screening<br>among migrants from regions with low HBV prevalence.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background: A significant portion of individuals with hepatitis B virus (HBV) or hepatitis C virus (HCV) in the Netherlands remain undiagnosed, with a majority from migrant backgrounds. Objectives: This study explored whether targeting HBV\/HCV screening among individuals with metabolic risk factors enhances screening efficacy within a diverse ethnic cohort. Methods: Participants from six ethnic backgrounds [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":true},"publications_year":[21],"thema":[44],"class_list":["post-1657","publicatie","type-publicatie","status-publish","hentry","publications_year-21","thema-infectious-disease"],"acf":[],"_links":{"self":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publicatie\/1657","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publicatie"}],"about":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/types\/publicatie"}],"wp:attachment":[{"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/media?parent=1657"}],"wp:term":[{"taxonomy":"publications_year","embeddable":true,"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/publications_year?post=1657"},{"taxonomy":"thema","embeddable":true,"href":"https:\/\/heliusstudy.nl\/en\/wp-json\/wp\/v2\/thema?post=1657"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}