Researchers

24,780 baseline participants

11,035 follow-up participants

21,000 baseline biological samples

Publications

Since 2011, more than 200 scientific articles based on the HELIUS data have been published. Below you can find, filter and read them.

Filters

Theme

Year

The Healthy Life in an Urban Setting (HELIUS) study in Amsterdam, The Netherlands: cohort update 2024 and key findings

Year: 2024
Authors: Galenkamp H, Koopman AD, van der Zwan JE, van den Born BJ, Lok A, Moll van Charante EP, Prins M, Verhoeff A, Zwinderman AH, Stronks K

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Year: 2025
Authors: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

The association and contribution of gender-related characteristics to prevalent chronic kidney disease in women and men in a multi-ethnic population – The HELIUS study

Year: 2025
Authors: Vosters TG, Kingma FM, Stel VS, Jager KJ, van Ittersum FJ, van den Born BJH, Vogt L, van Valkengoed IGM

Midlife dementia risk scores in a multi-ethnic population in the Netherlands: the HELIUS study

Year: 2025
Authors: Lindhout J, van der Endt AR, Hoevenaar-Blom MP, van Dalen JW, Deckers K, Geerlings MI, Galenkamp H, Richard E, Moll van Charante EP

Autonomic cardiac control independently predicts incident hypertension and systolic blood pressure in a multi-ethnic population: The HELIUS study

Year: 2025
Authors: Bouwmeester TA, Vriend EMC, Galenkamp H, Westerhof BE, Collard D, van den Born BJH

Antihypertensive Medication Category Prescriptions and Blood Pressure Control in African Surinamese and Ghanaian Migrants with Hypertension in Amsterdam, The Netherlands: The HELIUS Study

Year: 2025
Authors: van Apeldoorn JAN, Jansen L, Hoevenaar-Blom MP, Harskamp RE, Galenkamp H, van den Born BJH, Agyemang C, Richard E, Moll van Charante EP

Creatine Kinase and New-Onset Hypertension: a 10-Year Follow-Up Study

Year: 2025
Authors: Brewster LM, van den Born BJ, Galenkamp H, van Montfrans GA

The interplay of alcohol use symptoms and sociodemographic factors in the HELIUS study: A network perspective

Year: 2025
Authors: Huth KBS, Zavlis O, Luigjes J, Galenkamp H, Lok A, Stronks K, Bockting CLH, Goudriaan A, Marsman M, van Holst RJ

Chest pain in a multi-ethnic population: A community-based study on sex differences in chest pain prevalence and care contacts

Year: 2025
Authors: Hummel B, Harskamp RE, Vester E, Galenkamp H, Mommersteeg PMC, van Valkengoed IGM, namens het IMPRESS consortium

Vegetarian diet and kidney function in women and men from different ethnic groups: The HEalthy Life in an Urban Setting (HELIUS) study

Year: 2025
Authors: Smits RLA, Vosters TG, Vogt L, Galenkamp H, Nicolaou M, van Valkengoed IGM

About HELIUS

The HELIUS study is a prospective cohort study on health and health care among an urban multi-ethnic population.

The aim of the HELIUS study is to gain insight in the biological, psychological and social causes of the unequal burden of disease across ethnic groups, and ultimately enable the improvement of health care and prevention strategies. The study is being carried out in Amsterdam, the Netherlands, and is an initiative of Amsterdam UMC and the Public Health Service of Amsterdam (GGD Amsterdam).

The HELIUS study focuses on three primary research areas:

  • Cardiovascular diseases (including diabetes)
  • Mental disorders
  • Infectious diseases

Baseline data collection took place in 2011-2015. Nearly 25.000 participants of Turkish, Moroccan, South-Asian Surinamese, African Surinamese, Ghanaian and Dutch origin were included in the study. Data were collected through a questionnaire/interview and a physical examination. Biological samples were obtained during study visits. In 2019 – 2022, all HELIUS participants were invited for follow-up measurements. Again, a physical examination was performed, including the collection of biological samples.

For more information on the study design and data collection, we refer to the following papers:

Collaboration

HELIUS has an open policy in regard to collaboration with research groups.

Researchers from various departments of Amsterdam UMC and the GGD Amsterdam collaborate in the HELIUS study. In addition, we are open to proposals of collaboration with external research groups.

  • Before access to data is provided, all researchers should carefully read and must adhere to the HELIUS Collaboration Policy.
  • In brief, a research proposal or publication proposal must be developed following the proposal formats, which can be found in the Collaboration Policy.
  • All proposals should then be submitted to the HELIUS Scientific Coordinator (heliuscoordinator@amsterdamumc.nl). The proposals are discussed in the HELIUS Executive Board regarding their study aims, overlap with ongoing studies, logistic consequences and financial contributions.
  • After approval of the proposal by the HELIUS Executive Board, the collaborative research project is embedded in one of the three research areas supervised by the specific HELIUS Theme Leader.

Linkages

Several linkages have been established with national or regional registries in the Netherlands, to enrich the data:

Consortia

We collaborate with multiple national and international consortia.

FAQ researchers

Who can collaborate?

Researchers affiliated with a Dutch or international research institute may request data or samples to conduct a study that fits within the general aims of HELIUS.

Proposals regarding scientific collaboration should be submitted to the Scientific Coordinator, preferably after consulting the relevant Theme Leader. The proposals will then be considered by the HELIUS Executive Board, on the basis of: 1. compatibility with the general objectives of the HELIUS study, 2. the quality of the research proposal, 3. possible overlap with other cohort studies, 4. the use of biological material, 5. logistical feasibility and 6. the (financial) contribution to be made.

Yes, for access to data and biomaterial we follow the procedures as set out in the HELIUS Collaboration Policy, which you can download here.

Onze partners