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Researchers

24,780 baseline participants

11,035 follow-up participants

21,000 baseline biological samples

Publications

Since 2011, more than 200 scientific articles based on the HELIUS data have been published. Below you can find, filter and read them.

Filters

Theme

Year

Sex and ethnic differences in unrecognized myocardial infarctions: Observations on recognition and preventive therapies from the multiethnic population-based HELIUS cohort

Year: 2024
Authors: Hummel B, van Oortmerssen JAE, Borst CM, Harskamp RE, Galenkamp H, Postema PG, van Valkengoed IGM; IMPRESS consortium

Plasma sphingolipids mediate the association between gut microbiome composition and type 2 diabetes risk in the HELIUS cohort: a case-cohort study

Year: 2024
Authors: Overbeek MF, Rutters F, Nieuwdorp M, Davids M, van Valkengoed I, Galenkamp H, van den Born BJ, Beulens JWJ, Muilwijk M

Individual and neighborhood determinants of depressive symptoms in ethnic minorities in the urban HELIUS sample: a multi-level network perspective

Year: 2024
Authors: Huth K, van der Wal J, Zavlis O, Luigjes J, Lakerveld J, Galenkamp H, Lok A, Stronks K, Bockting C, Marsman M, Goudriaan A

Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: results from two observational, population-based microbiome studies

Year: 2024
Authors: Kullberg RFJ, Wikki I, Haak BW, Kauko A, Galenkamp H, Peters-Sengers H, Butler JM, Havulinna AS, Palmu J, McDonald D, Benchraka C, Abdel-Aziz MI, Prins M, Maitland van der Zee AH, van den Born BJ, Jousilahti P, de Vos WM, Salomaa V, Knight R, Lahti L, Nieuwdorp M, Niiranen T, Wiersinga WJ

Phylogeny and disease associations of a widespread and ancient intestinal bacteriophage lineage

Year: 2024
Authors: de Jonge PA, van den Born BH, Zwinderman AH, Nieuwdorp M, Dutilh BE, Herrema H

The association of obesogenic environments with weight status, blood pressure, and blood lipids: A cross-sectional pooled analysis across five cohorts

Year: 2024
Authors: Meijer P, Lam TM, Vaartjes I, Moll van Charante E, Galenkamp H, Koster A, van den Hurk K, den Braver NR, Blom MT, de Jong T, Grobbee DE, Beulens JW, Lakerveld J; GECCO consortium

Adding ethnicity to cardiovascular risk prediction: External validation and model updating of SCORE2 using data from the HELIUS population cohort

Year: 2024
Authors: van Apeldoorn JAN, Hageman SHJ, Harskamp RE, Agyemang C, van den Born BH, van Dalen JW, Galenkamp H, Hoevenaar-Blom MP, Richard E, van Valkengoed IGM, Visseren FLJ, Dorresteijn JAN, Moll van Charante EP

Differences in SARS-CoV-2 antibody prevalence at the end of the pre-vaccination period between age groups: A cross-sectional analysis of the multi-ethnic population-based HELIUS study

Year: 2024
Authors: Bolijn R, Spijkerman AMW, Galenkamp H, Blokstra A, Coyer L, Boyd A, Prins M, Stronks K

The association of overweight, obesity, and long-term obesity with SARS-CoV-2 infection: a meta-analysis of 9 population-based cohorts from the Netherlands Cohorts Consortium

Year: 2024
Authors: Loef B, Boer JMA, Beekman M, Campman SL, Hoogendijk EO, Huider F, Pagen DME, Splinter MJ, van der Velde JHPM, Boomsma DI, Dagnelie PC, van Dongen J, de Geus EJC, Huisman M, Arfan Ikram M, Koster A, Licher S, Mierau JO, de Mutsert R, Picavet HSJ, Rosendaal FR, Schram MT, Slagboom PE, van der Spoel E, Stronks K, Verschuren WMM, van den Berg SW; Lifelines Corona Research initiative

The Association between Post-Traumatic Stress Disorder and Problematic Alcohol and Cannabis Use in a Multi-Ethnic Cohort in The Netherlands: The HELIUS Study

Year: 2024
Authors: Kühner C, Will JP, Lortye SA, Galenkamp H, Lok A, van Zuiden M, Arntz AR, Thomaes K, Goudriaan AE, de Waal MM

About HELIUS

The HELIUS study is a prospective cohort study on health and health care among an urban multi-ethnic population.

The aim of the HELIUS study is to gain insight in the biological, psychological and social causes of the unequal burden of disease across ethnic groups, and ultimately enable the improvement of health care and prevention strategies. The study is being carried out in Amsterdam, the Netherlands, and is an initiative of Amsterdam UMC and the Public Health Service of Amsterdam (GGD Amsterdam).

The HELIUS study focuses on three primary research areas:

  • Cardiovascular diseases (including diabetes)
  • Mental disorders
  • Infectious diseases

Baseline data collection took place in 2011-2015. Nearly 25.000 participants of Turkish, Moroccan, South-Asian Surinamese, African Surinamese, Ghanaian and Dutch origin were included in the study. Data were collected through a questionnaire/interview and a physical examination. Biological samples were obtained during study visits. In 2019 – 2022, all HELIUS participants were invited for follow-up measurements. Again, a physical examination was performed, including the collection of biological samples.

For more information on the study design and data collection, we refer to the following papers:

Collaboration

HELIUS has an open policy in regard to collaboration with research groups.

Researchers from various departments of Amsterdam UMC and the GGD Amsterdam collaborate in the HELIUS study. In addition, we are open to proposals of collaboration with external research groups.

  • Before access to data is provided, all researchers should carefully read and must adhere to the HELIUS Collaboration Policy.
  • In brief, a research proposal or publication proposal must be developed following the proposal formats, which can be found in the Collaboration Policy.
  • All proposals should then be submitted to the HELIUS Scientific Coordinator (heliuscoordinator@amsterdamumc.nl). The proposals are discussed in the HELIUS Executive Board regarding their study aims, overlap with ongoing studies, logistic consequences and financial contributions.
  • After approval of the proposal by the HELIUS Executive Board, the collaborative research project is embedded in one of the three research areas supervised by the specific HELIUS Theme Leader.

Linkages

Several linkages have been established with national or regional registries in the Netherlands, to enrich the data:

Consortia

We collaborate with multiple national and international consortia.

FAQ researchers

Who can collaborate?

Researchers affiliated with a Dutch or international research institute may request data or samples to conduct a study that fits within the general aims of HELIUS.

Proposals regarding scientific collaboration should be submitted to the Scientific Coordinator, preferably after consulting the relevant Theme Leader. The proposals will then be considered by the HELIUS Executive Board, on the basis of: 1. compatibility with the general objectives of the HELIUS study, 2. the quality of the research proposal, 3. possible overlap with other cohort studies, 4. the use of biological material, 5. logistical feasibility and 6. the (financial) contribution to be made.

Data collection consists of questionnaires, physical examination and collection of biomaterial. For an overview, see:

Yes, for access to data and biomaterial we follow the procedures as set out in the HELIUS Collaboration Policy, which you can download here.

Onze partners

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