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Researchers

24,780 baseline participants

11,035 follow-up participants

21,000 baseline biological samples

Publications

Since 2011, more than 200 scientific articles based on the HELIUS data have been published. Below you can find, filter and read them.

Filters

Theme

Year

Cardiovascular Risk Estimation Based on Country-of-Birth- and Country-of-Residence-Specific Scores among Migrants in the Netherlands: The HELIUS Study

Year: 2023
Authors: Osei-Yeboah J, Moll van Charante EP, Kengne AP, Owusu-Dabo E, van den Born BH, Galenkamp-van der Ploeg H, Chilunga FP, Boateng D, Motazedi E, Agyemang C

Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants

Year: 2023
Authors: Souama C, Lamers F, Milaneschi Y, Vinkers CH, Defina S, Garvert L, Stein F, Woofenden T, Brosch K, Dannlowski U, Galenkamp H, de Graaf R, Jaddoe VWV, Lok A, van Rijn BB, Völzke H, Cecil CAM, Felix JF, Grabe HJ, Kircher T, Lekadir K, Have MT, Walton E, Penninx BWJH; EarlyCause consortium

Ethnic differences in blood pressure levels over time: the HELIUS study

Year: 2023
Authors: Vriend EMC, Wever BE, Bouwmeester TA, Agyemang C, Franco OH, Galenkamp H, Moll van Charante EP, Zwinderman AH, Collard D, van den Born BH

Psychosocial factors may serve as additional eligibility criteria for cardiovascular risk screening in women and men in a multi-ethnic population: The HELIUS study

Year: 2023
Authors: Hummel B, Harskamp RE, Bolijn R, Moll van Charante EP, Galenkamp H, Mommersteeg PMC, van Valkengoed IGM

Ancestral and environmental patterns in the association between triglycerides and other cardiometabolic risk factors

Year: 2023
Authors: Meeks KAC, Bentley AR, Agyemang C, Galenkamp H, van den Born BH, Hanssen NMJ, Doumatey AP, Adeyemo AA, Rotimi CN

Automated analysis of finger blood pressure recordings provides insight in determinants of baroreflex sensitivity and heart rate variability-the HELIUS study

Year: 2023
Authors: Collard D, Westerhof BE, Karemaker JM, Stok WJ, Postema PG, Krediet CTP, Vogt L, van den Born BJH

Gut microbiome transitions across generations in different ethnicities in an urban setting-the HELIUS study

Year: 2023
Authors: van der Vossen EWJ, Davids M, Bresser LRF, Galenkamp H, van den Born BH, Zwinderman AH, Levin E, Nieuwdorp M, de Goffau MC

Unexploited potential of risk factor treatment in patients with atherosclerotic cardiovascular disease

Year: 2023
Authors: van Trier TJ, Snaterse M, Hageman SHJ, Ter Hoeve N, Sunamura M, Moll van Charante EP, Galenkamp H, Deckers JW, Martens FMAC, Visseren FLJ, Scholte Op Reimer WJM, Peters RJG, Jørstad HT

Sex differences in associations of plasma metabolites with blood pressure and heart rate variability: The HELIUS study

Year: 2023
Authors: Verhaar BJH, Mosterd CM, Collard D, Galenkamp H, Muller M, Rampanelli E, van Raalte DH, Nieuwdorp M, van den Born BH

Autonomic regulation in different hypertensive phenotypes – the HELIUS study

Year: 2023
Authors: Collard D, Vriend EMC, Galenkamp H, Moll van Charante EP, Vogt L, Westerhof BE, van den Born BJH

About HELIUS

The HELIUS study is a prospective cohort study on health and health care among an urban multi-ethnic population.

The aim of the HELIUS study is to gain insight in the biological, psychological and social causes of the unequal burden of disease across ethnic groups, and ultimately enable the improvement of health care and prevention strategies. The study is being carried out in Amsterdam, the Netherlands, and is an initiative of Amsterdam UMC and the Public Health Service of Amsterdam (GGD Amsterdam).

The HELIUS study focuses on three primary research areas:

  • Cardiovascular diseases (including diabetes)
  • Mental disorders
  • Infectious diseases

Baseline data collection took place in 2011-2015. Nearly 25.000 participants of Turkish, Moroccan, South-Asian Surinamese, African Surinamese, Ghanaian and Dutch origin were included in the study. Data were collected through a questionnaire/interview and a physical examination. Biological samples were obtained during study visits. In 2019 – 2022, all HELIUS participants were invited for follow-up measurements. Again, a physical examination was performed, including the collection of biological samples.

For more information on the study design and data collection, we refer to the following papers:

Collaboration

HELIUS has an open policy in regard to collaboration with research groups.

Researchers from various departments of Amsterdam UMC and the GGD Amsterdam collaborate in the HELIUS study. In addition, we are open to proposals of collaboration with external research groups.

  • Before access to data is provided, all researchers should carefully read and must adhere to the HELIUS Collaboration Policy.
  • In brief, a research proposal or publication proposal must be developed following the proposal formats, which can be found in the Collaboration Policy.
  • All proposals should then be submitted to the HELIUS Scientific Coordinator (heliuscoordinator@amsterdamumc.nl). The proposals are discussed in the HELIUS Executive Board regarding their study aims, overlap with ongoing studies, logistic consequences and financial contributions.
  • After approval of the proposal by the HELIUS Executive Board, the collaborative research project is embedded in one of the three research areas supervised by the specific HELIUS Theme Leader.

Linkages

Several linkages have been established with national or regional registries in the Netherlands, to enrich the data:

Consortia

We collaborate with multiple national and international consortia.

FAQ researchers

Who can collaborate?

Researchers affiliated with a Dutch or international research institute may request data or samples to conduct a study that fits within the general aims of HELIUS.

Proposals regarding scientific collaboration should be submitted to the Scientific Coordinator, preferably after consulting the relevant Theme Leader. The proposals will then be considered by the HELIUS Executive Board, on the basis of: 1. compatibility with the general objectives of the HELIUS study, 2. the quality of the research proposal, 3. possible overlap with other cohort studies, 4. the use of biological material, 5. logistical feasibility and 6. the (financial) contribution to be made.

Data collection consists of questionnaires, physical examination and collection of biomaterial. For an overview, see:

Yes, for access to data and biomaterial we follow the procedures as set out in the HELIUS Collaboration Policy, which you can download here.

Onze partners

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