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Researchers

24,780 baseline participants

11,035 follow-up participants

21,000 baseline biological samples

Publications

Since 2011, more than 200 scientific articles based on the HELIUS data have been published. Below you can find, filter and read them.

Filters

Theme

Year

Validation of the enhanced liver fibrosis (ELF)-test in heparinized and EDTA plasma for use in reflex testing algorithms for metabolic dysfunction-associated steatotic liver disease (MASLD)

Year: 2024
Authors: van Son KC, van Dijk AM, Driessen S, Mak AL, Witjes JJ, Houttu VAT, Zwirs D, Nieuwdorp M, van den Born BJH, Fischer JC, Tushuizen ME, Drenth JPH, Hamer HM, Beuers UHW, Verheij J, Holleboom AG

Mid-life association between cardiovascular risk factors and cerebral blood flow in a multi-ethnic population

Year: 2024
Authors: Vriend EMC, Dijsselhof MBJ, Bouwmeester TA, Franco OH, Galenkamp H, Collard D, Nederveen AJ, van den Born BJH, Mutsaerts HJMM

Machine learning analysis of sex and menopausal differences in the gut microbiome in the HELIUS study

Year: 2024
Authors: Vriend EMC, Galenkamp H, Herrema H, Nieuwdorp M, van den Born BJH, Verhaar BJH

Effects of antihypertensives with and without IL-6 lowering properties on long-term blood pressure control: The prospective HELIUS cohort

Year: 2024
Authors: Batuo H, van der Linden E, Galenkamp H, Moll van Charante E, van der Born BJ, Chilunga FP

ECG Changes during Adult Life in Fabry Disease: Results from a Large Longitudinal Cohort Study

Year: 2023
Authors: El Sayed M, Postema PG, Datema M, van Dussen L, Kors JA, Ter Haar CC, Bleijendaal H, Galenkamp H, van den Born BH, Hollak CEM, Langeveld M

Perceived ethnic discrimination, suicidal ideation and mastery in a multi-ethnic cohort: the HELIUS study

Year: 2023
Authors: Willemen FEM, Heuschen CBBCM, Zantvoord JB, Galenkamp H, de Wit MAS, Zwinderman AH, Denys DAJP, Bockting CLH, Stronks K, Lok A

The contribution of smoking to differences in cardiovascular disease incidence between men and women across six ethnic groups in Amsterdam, the Netherlands: The HELIUS study

Year: 2023
Authors: Bolijn R, Muilwijk M, Nicolaou M, Galenkamp H, Stronks K, Tan HL, Kunst AE, van Valkengoed IGM

FHL2 Genetic Polymorphisms and Pro-Diabetogenic Lipid Profile in the Multiethnic HELIUS Cohort

Year: 2023
Authors: Habibe JJ, Boulund U, Clemente-Olivo MP, de Vries CJM, Eringa EC, Nieuwdorp M, Ferwerda B, Zwinderman K, van den Born BH, Galenkamp H, van Raalte DH

Are male patients undergoing bariatric surgery less healthy than female patients?

Year: 2023
Authors: van Olst N, Reiber BMM, Vink MRA, Gerdes VEA, Galenkamp H, van der Peet DL, van Rijswijk AS, Bruin SC

Intent to vaccinate against SARS-CoV-2 and its determinants across six ethnic groups living in Amsterdam, the Netherlands: A cross-sectional analysis of the HELIUS study

Year: 2023
Authors: Campman SL, van Rossem G, Boyd A, Coyer L, Schinkel J, Agyemang C, Galenkamp H, Koopman ADM, Leenstra T, Schim van der Loeff M, Moll van Charante EP, van den Born BH, Lok A, Verhoeff A, Zwinderman AH, Jurriaans S, Stronks K, Prins M

About HELIUS

The HELIUS study is a prospective cohort study on health and health care among an urban multi-ethnic population.

The aim of the HELIUS study is to gain insight in the biological, psychological and social causes of the unequal burden of disease across ethnic groups, and ultimately enable the improvement of health care and prevention strategies. The study is being carried out in Amsterdam, the Netherlands, and is an initiative of Amsterdam UMC and the Public Health Service of Amsterdam (GGD Amsterdam).

The HELIUS study focuses on three primary research areas:

  • Cardiovascular diseases (including diabetes)
  • Mental disorders
  • Infectious diseases

Baseline data collection took place in 2011-2015. Nearly 25.000 participants of Turkish, Moroccan, South-Asian Surinamese, African Surinamese, Ghanaian and Dutch origin were included in the study. Data were collected through a questionnaire/interview and a physical examination. Biological samples were obtained during study visits. In 2019 – 2022, all HELIUS participants were invited for follow-up measurements. Again, a physical examination was performed, including the collection of biological samples.

For more information on the study design and data collection, we refer to the following papers:

Collaboration

HELIUS has an open policy in regard to collaboration with research groups.

Researchers from various departments of Amsterdam UMC and the GGD Amsterdam collaborate in the HELIUS study. In addition, we are open to proposals of collaboration with external research groups.

  • Before access to data is provided, all researchers should carefully read and must adhere to the HELIUS Collaboration Policy.
  • In brief, a research proposal or publication proposal must be developed following the proposal formats, which can be found in the Collaboration Policy.
  • All proposals should then be submitted to the HELIUS Scientific Coordinator (heliuscoordinator@amsterdamumc.nl). The proposals are discussed in the HELIUS Executive Board regarding their study aims, overlap with ongoing studies, logistic consequences and financial contributions.
  • After approval of the proposal by the HELIUS Executive Board, the collaborative research project is embedded in one of the three research areas supervised by the specific HELIUS Theme Leader.

Linkages

Several linkages have been established with national or regional registries in the Netherlands, to enrich the data:

Consortia

We collaborate with multiple national and international consortia.

FAQ researchers

Who can collaborate?

Researchers affiliated with a Dutch or international research institute may request data or samples to conduct a study that fits within the general aims of HELIUS.

Proposals regarding scientific collaboration should be submitted to the Scientific Coordinator, preferably after consulting the relevant Theme Leader. The proposals will then be considered by the HELIUS Executive Board, on the basis of: 1. compatibility with the general objectives of the HELIUS study, 2. the quality of the research proposal, 3. possible overlap with other cohort studies, 4. the use of biological material, 5. logistical feasibility and 6. the (financial) contribution to be made.

Data collection consists of questionnaires, physical examination and collection of biomaterial. For an overview, see:

Yes, for access to data and biomaterial we follow the procedures as set out in the HELIUS Collaboration Policy, which you can download here.

Onze partners

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